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Symbol Name ID |
Slfn4
schlafen 4 MGI:1329010 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
increased T cell apoptosis |
abnormal T cell proliferation |
decreased T cell proliferation |
increased neutrophil cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased monocyte cell number |
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology |
abnormal leukocyte physiology |
decreased IgG level |
abnormal T cell activation |
abnormal interleukin level |
abnormal tumor necrosis factor level |
impaired humoral immune response |
decreased susceptibility to bacterial infection |
increased susceptibility to bacterial infection |
increased susceptibility to bacterial infection induced morbidity/mortality |
increased susceptibility to Herpesvirales infection induced morbidity/mortality |
increased susceptibility to Riboviria infection |
decreased response to antigen |
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| Availability | Mouse Genotype | |||||||||||||||||||||
| Slfn1tm1Aki/Slfn1tm1Aki | * | |||||||||||||||||||||
| Slfn2m1Btlr/Slfn2m1Btlr | ||||||||||||||||||||||
| Slfn2m2Btlr/Slfn2m2Btlr | ||||||||||||||||||||||
| Slfn3tm1Aki/Slfn3tm1Aki | * | |||||||||||||||||||||
| Slfn4tm1c(EUCOMM)Wtsi/Slfn4tm1c(EUCOMM)Wtsi Gli1tm3(cre/ERT2)Alj/Gli1+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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